Inherent Properties, Identifiers and References
ChemSpider ID: 1078
Empirical Formula: C4H6O4
Molecular Weight: 118.088
Nominal Mass: 118 Da
Average Mass: 118.088 Da
Monoisotopic Mass: 118.026609 Da
Quick Links: Permalink Similar Isomers
Systematic Name: succinic acid
SMILES: O=C(O)CCC(=O)O
InChI: InChI=1/C4H6O4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)(H,7,8)
InChIKey: KDYFGRWQOYBRFD-UHFFFAOYAC
(Details...) Original Reference(s)
Succinic acid (IUPAC systematic name: butanedioic acid; historically known as spirit of amber) is a dicarboxylic acid. Succinate plays a biochemical role in the citric acid cycle. Read more... or Edit at Wikipedia...
Data SourceExternal ID(s)
UsefulChemUC0071
Disclaimer (Details...) Supplemental Information

User Data

  • experimental physchem properties
    • Melting Point: 185 C
    • Boiling Point: 235 C
  • miscellaneous
    • Appearance: colourless odourless prisms or white crystalline powder
    • Stability: Stable. Substances to be avoided include strong bases,strong oxidizing agents. Combustible.
    • Toxicity: ORL-RAT LD50 2260 mg kg-1, IPR-MUS LD50 2702 mg kg-1, IVN-MUS LD50 1400 mg kg-1
    • Safety: Safety glasses. Adequate ventilation.
(Details...) Names and Synonyms

Validated by Experts, Validated by Users, Non-Validated, Removed by Users, Redirected by Users, Redirect Approved by Experts

2,3-Dihyd​robutaned​ioic acid

203-740-4 [EINECS/ELINCS]

hydrogen ​succinate

1,2-Ethan​edicarbox​ylate

1,4-Butan​edioate

Dihydrofu​marate

1,2-Ethan​edicarbox​ylic acid

1,4-Butan​edioic ac​id

1,4-BUTAN​EDIOIC AC​ID (SUCC​INIC ACID)

110-15-6 [RN]

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(Details...) Database ID(s)

Validated by Experts, Validated by Users, Non-Validated, Removed by Users, Redirected by Users, Redirect Approved by Experts

14078_FLU​KA

14079_FLU​KA

398055_SI​AL

A 12084

AI3-06297

AIDS017693

AIDS-0176​93

BRN 17540​69

C00042

CHEBI:157​41

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(Details...) Predicted Properties
LogP: ACD/LogP: -0.59
XLogP: -0.70
ALOGPS: -0.53
# of Rule of 5 Violations: 0
ACD/LogD (pH 5.5): -2.15 ACD/LogD (pH 7.4): -5.13
ACD/BCF (pH 5.5): 1 ACD/BCF (pH 7.4): 1
ACD/KOC (pH 5.5): 1 ACD/KOC (pH 7.4): 1
#H bond acceptors: 4 #H bond donors: 2
#Freely Rotating Bonds: 3 Polar Surface Area: 52.6 Å2
Index of Refraction: 1.477 Molar Refractivity: 23.7 cm3
Molar Volume: 83.8 cm3 Polarizability: 9.39 10-24cm3
Surface Tension: 61.6 dyne/cm Density: 1.408 g/cm3
Flash Point: 110.9 °C Enthalpy of Vaporization: 52.09 kJ/mol
Boiling Point: 236.1 °C at 760 mmHg Vapour Pressure: 0.0165 mmHg at 25°C
            
 Log Octanol-Water Partition Coef (SRC):
    Log Kow (KOWWIN v1.67 estimate) =  -0.75
    Log Kow (Exper. database match) =  -0.59
       Exper. Ref:  Hansch,C et al. (1995)

 Boiling Pt, Melting Pt, Vapor Pressure Estimations (MPBPWIN v1.42):
    Boiling Pt (deg C):  280.41  (Adapted Stein & Brown method)
    Melting Pt (deg C):  83.27  (Mean or Weighted MP)
    VP(mm Hg,25 deg C):  0.000108  (Modified Grain method)
    MP  (exp database):  188 deg C
    BP  (exp database):  235 dec deg C
    VP  (exp database):  1.91E-07 mm Hg at 25 deg C
    Subcooled liquid VP: 7.82E-006 mm Hg (25 deg C, exp database VP )

 Water Solubility Estimate from Log Kow (WSKOW v1.41):
    Water Solubility at 25 deg C (mg/L):  8.079e+005
       log Kow used: -0.59 (expkow database)
       no-melting pt equation used
     Water Sol (Exper. database match) =  8.32e+004 mg/L (25 deg C)
        Exper. Ref:  YALKOWSKY,SH & DANNENFELSER,RM (1992)

 Water Sol Estimate from Fragments:
    Wat Sol (v1.01 est) =  4.0519e+005 mg/L
    Wat Sol (Exper. database match) =  83200.00
       Exper. Ref:  YALKOWSKY,SH & DANNENFELSER,RM (1992)

 ECOSAR Class Program (ECOSAR v0.99h):
    Class(es) found:
       Neutral Organics-acid

 Henrys Law Constant (25 deg C) [HENRYWIN v3.10]:
   Bond Method :   5.41E-012  atm-m3/mole
   Group Method:   4.06E-013  atm-m3/mole
   Exper Database: 3.57E-13  atm-m3/mole
 Henrys LC [VP/WSol estimate using EPI values]:  2.077E-011 atm-m3/mole

 Log Octanol-Air Partition Coefficient (25 deg C) [KOAWIN v1.10]:
  Log Kow used:  -0.59  (exp database)
  Log Kaw used:  -10.836  (exp database)
      Log Koa (KOAWIN v1.10 estimate):  10.246
      Log Koa (experimental database):  None

 Probability of Rapid Biodegradation (BIOWIN v4.10):
   Biowin1 (Linear Model)         :   0.8367
   Biowin2 (Non-Linear Model)     :   0.9320
 Expert Survey Biodegradation Results:
   Biowin3 (Ultimate Survey Model):   3.6674  (days-weeks  )
   Biowin4 (Primary Survey Model) :   4.4485  (hours-days  )
 MITI Biodegradation Probability:
   Biowin5 (MITI Linear Model)    :   0.8220
   Biowin6 (MITI Non-Linear Model):   0.9042
 Anaerobic Biodegradation Probability:
   Biowin7 (Anaerobic Linear Model):  1.2616
 Ready Biodegradability Prediction:   YES

Hydrocarbon Biodegradation (BioHCwin v1.01):
    Structure incompatible with current estimation method!

 Sorption to aerosols (25 Dec C)[AEROWIN v1.00]:
  Vapor pressure (liquid/subcooled):  0.00104 Pa (7.82E-006 mm Hg)
  Log Koa (Koawin est  ): 10.246
   Kp (particle/gas partition coef. (m3/ug)):
       Mackay model           :  0.00288 
       Octanol/air (Koa) model:  0.00433 
   Fraction sorbed to airborne particulates (phi):
       Junge-Pankow model     :  0.0941 
       Mackay model           :  0.187 
       Octanol/air (Koa) model:  0.257 

 Atmospheric Oxidation (25 deg C) [AopWin v1.92]:
   Hydroxyl Radicals Reaction:
      OVERALL OH Rate Constant =   2.7632 E-12 cm3/molecule-sec
      Half-Life =     3.871 Days (12-hr day; 1.5E6 OH/cm3)
      Half-Life =    46.450 Hrs
   Ozone Reaction:
      No Ozone Reaction Estimation
   Fraction sorbed to airborne particulates (phi): 0.141 (Junge,Mackay)
    Note: the sorbed fraction may be resistant to atmospheric oxidation

 Soil Adsorption Coefficient (PCKOCWIN v1.66):
      Koc    :  6.314
      Log Koc:  0.800 

 Aqueous Base/Acid-Catalyzed Hydrolysis (25 deg C) [HYDROWIN v1.67]:
    Rate constants can NOT be estimated for this structure!

 Bioaccumulation Estimates from Log Kow (BCFWIN v2.17):
   Log BCF from regression-based method = 0.500 (BCF = 3.162)
       log Kow used: -0.59 (expkow database)

 Volatilization from Water:
    Henry LC:  3.57E-013 atm-m3/mole  (Henry experimental database)
    Half-Life from Model River: 1.782E+009  hours   (7.426E+007 days)
    Half-Life from Model Lake : 1.944E+010  hours   (8.101E+008 days)

 Removal In Wastewater Treatment:
    Total removal:               1.85  percent
    Total biodegradation:        0.09  percent
    Total sludge adsorption:     1.76  percent
    Total to Air:                0.00  percent
      (using 10000 hr Bio P,A,S)

 Level III Fugacity Model:
           Mass Amount    Half-Life    Emissions
            (percent)        (hr)       (kg/hr)
   Air       1.26e-005       92.9         1000       
   Water     34.4            208          1000       
   Soil      65.6            416          1000       
   Sediment  0.0596          1.87e+003    0          
     Persistence Time: 388 hr