1 hit(s) found in 0.47 seconds
Search term: KWOLFJPFCHCOCG
Found by InChIKey (skeleton match)
Inherent Properties, Identifiers and References
ChemSpider ID: 7132
Empirical Formula: C8H8O
Molecular Weight: 120.1485
Nominal Mass: 120 Da
Average Mass: 120.1485 Da
Monoisotopic Mass: 120.057515 Da
Quick Links: Permalink Similar Isomers
Systematic Name: 1-phenylethanone
SMILES: O=C(c1ccccc1)C
InChI: InChI=1/C8H8O/c1-7(9)8-5-3-2-4-6-8/h2-6H,1H3
InChIKey: KWOLFJPFCHCOCG-UHFFFAOYAT
(Details...) Wikipedia Article(s)
Acetophenone is a crystalline ketone that is used as a solvent for cellulose ethers and esters in the manufacture of alcohol-soluble resins. These in turn are used in perfume. Acetophenone is used to create fragrances that resemble almond, cherry, honeysuckle, jasmine, and strawberry. It is used in chewing gum. It can be found naturally in apple, cheese, apricot, banana, beef and cauliflower. This chemical may be obtained by the dry distillation of a mixture of the calcium salts of acetic and benzoic acids. Currently acetophenone mainly comes as a by-product of the phenol-acetone synthesis in the cumene oxidation process. At one time it was used as a hypnotic under the name of hypnone. Read more... or Edit at Wikipedia...
(Details...) Original Reference(s)
Data Source External ID(s)
UsefulChem UC0228
Disclaimer (Details...) Supplemental Information

User Data

  • experimental physchem properties
    • Melting Point: 19 C
    • Boiling Point: 202
    • Boiling Point: 202 C
    • Flash Point: 82 C
    • Specific Gravity: 1.022-1.028
    • Refraction Index: 1.530-1.535
    • logP: 1.58
  • miscellaneous
    • Appearance: colourless liquid which will solidify at 20°C
    • Appearance: yellow liquid
    • Stability: Stable. Incompatible with strong oxidizing agents, strong bases,strong reducing agents. Combustible.
    • Toxicity: ORL-RAT LD50 815 mg kg-1
    • Safety: Safety glasses. Adequate ventilation.
(Details...) Names and Synonyms

Validated by Experts, Validated by Users, Non-Validated, Removed by Users, Redirected by Users, Redirect Approved by Experts

1-phenyle​than-1-one

202-708-7 [EINECS/ELINCS]

Acetofenon [Czech]

acetophen​one [Wiki]

Hypnon

Oxophenyl​ethane

1-Phenyl-​1-ethanone

1-Phenyle​thanone

249-854-8 [EINECS/ELINCS]

29797-40-8 [RN]

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(Details...) Database ID(s)

Validated by Experts, Validated by Users, Non-Validated, Removed by Users, Redirected by Users, Redirect Approved by Experts

00790_FLU​KA

42163_FLU​KA

442438_SU​PELCO

A10701_AL​DRICH

AI3-00575

AI3-28597

AIDS017929

AIDS-0179​29

BRN 10994​07

c0117

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(Details...) Predicted Properties
LogP: ACD/LogP: 1.67
XLogP: 1.90
ALOGPS: 1.65
# of Rule of 5 Violations: 0
ACD/LogD (pH 5.5): 1.66 ACD/LogD (pH 7.4): 1.66
ACD/BCF (pH 5.5): 10.85 ACD/BCF (pH 7.4): 10.85
ACD/KOC (pH 5.5): 191.75 ACD/KOC (pH 7.4): 191.75
#H bond acceptors: 1 #H bond donors: 0
#Freely Rotating Bonds: 1 Polar Surface Area: 17.07 Å2
Index of Refraction: 1.511 Molar Refractivity: 36.28 cm3
Molar Volume: 120.9 cm3 Polarizability: 14.38 10-24cm3
Surface Tension: 34.1 dyne/cm Density: 0.993 g/cm3
Flash Point: 80.9 °C Enthalpy of Vaporization: 43.82 kJ/mol
Boiling Point: 202 °C at 760 mmHg Vapour Pressure: 0.299 mmHg at 25°C
            
 Log Octanol-Water Partition Coef (SRC):
    Log Kow (KOWWIN v1.67 estimate) =  1.67
    Log Kow (Exper. database match) =  1.58
       Exper. Ref:  Hansch,C et al. (1995)

 Boiling Pt, Melting Pt, Vapor Pressure Estimations (MPBPWIN v1.42):
    Boiling Pt (deg C):  189.81  (Adapted Stein & Brown method)
    Melting Pt (deg C):  -9.86  (Mean or Weighted MP)
    VP(mm Hg,25 deg C):  0.326  (Mean VP of Antoine & Grain methods)
    MP  (exp database):  20 deg C
    BP  (exp database):  202 deg C
    VP  (exp database):  3.97E-01 mm Hg at 25 deg C

 Water Solubility Estimate from Log Kow (WSKOW v1.41):
    Water Solubility at 25 deg C (mg/L):  4484
       log Kow used: 1.58 (expkow database)
       no-melting pt equation used
     Water Sol (Exper. database match) =  6130 mg/L (25 deg C)
        Exper. Ref:  SOUTHWORTH,GR & KELLER,JL (1986)

 Water Sol Estimate from Fragments:
    Wat Sol (v1.01 est) =  6148.7 mg/L
    Wat Sol (Exper. database match) =  6130.00
       Exper. Ref:  SOUTHWORTH,GR & KELLER,JL (1986)

 ECOSAR Class Program (ECOSAR v0.99h):
    Class(es) found:
       Neutral Organics

 Henrys Law Constant (25 deg C) [HENRYWIN v3.10]:
   Bond Method :   9.81E-006  atm-m3/mole
   Group Method:   1.09E-005  atm-m3/mole
   Exper Database: 1.04E-05  atm-m3/mole
 Henrys LC [VP/WSol estimate using EPI values]:  1.149E-005 atm-m3/mole

 Log Octanol-Air Partition Coefficient (25 deg C) [KOAWIN v1.10]:
  Log Kow used:  1.58  (exp database)
  Log Kaw used:  -3.371  (exp database)
      Log Koa (KOAWIN v1.10 estimate):  4.951
      Log Koa (experimental database):  None

 Probability of Rapid Biodegradation (BIOWIN v4.10):
   Biowin1 (Linear Model)         :   0.8253
   Biowin2 (Non-Linear Model)     :   0.9339
 Expert Survey Biodegradation Results:
   Biowin3 (Ultimate Survey Model):   2.9332  (weeks       )
   Biowin4 (Primary Survey Model) :   3.6571  (days-weeks  )
 MITI Biodegradation Probability:
   Biowin5 (MITI Linear Model)    :   0.5139
   Biowin6 (MITI Non-Linear Model):   0.6249
 Anaerobic Biodegradation Probability:
   Biowin7 (Anaerobic Linear Model):  0.1057
 Ready Biodegradability Prediction:   YES

Hydrocarbon Biodegradation (BioHCwin v1.01):
    Structure incompatible with current estimation method!

 Sorption to aerosols (25 Dec C)[AEROWIN v1.00]:
  Vapor pressure (liquid/subcooled):  52.9 Pa (0.397 mm Hg)
  Log Koa (Koawin est  ): 4.951
   Kp (particle/gas partition coef. (m3/ug)):
       Mackay model           :  5.67E-008 
       Octanol/air (Koa) model:  2.19E-008 
   Fraction sorbed to airborne particulates (phi):
       Junge-Pankow model     :  2.05E-006 
       Mackay model           :  4.53E-006 
       Octanol/air (Koa) model:  1.75E-006 

 Atmospheric Oxidation (25 deg C) [AopWin v1.92]:
   Hydroxyl Radicals Reaction:
      OVERALL OH Rate Constant =   1.8795 E-12 cm3/molecule-sec
      Half-Life =     5.691 Days (12-hr day; 1.5E6 OH/cm3)
      Half-Life =    68.292 Hrs
   Ozone Reaction:
      No Ozone Reaction Estimation
   Fraction sorbed to airborne particulates (phi): 3.29E-006 (Junge,Mackay)
    Note: the sorbed fraction may be resistant to atmospheric oxidation

 Soil Adsorption Coefficient (PCKOCWIN v1.66):
      Koc    :  46.2
      Log Koc:  1.665 

 Aqueous Base/Acid-Catalyzed Hydrolysis (25 deg C) [HYDROWIN v1.67]:
    Rate constants can NOT be estimated for this structure!

 Bioaccumulation Estimates from Log Kow (BCFWIN v2.17):
   Log BCF from regression-based method = -0.323 (BCF = 0.4749)
       log Kow used: 1.58 (expkow database)

 Volatilization from Water:
    Henry LC:  1.04E-005 atm-m3/mole  (Henry experimental database)
    Half-Life from Model River:      62.83  hours   (2.618 days)
    Half-Life from Model Lake :      777.3  hours   (32.39 days)

 Removal In Wastewater Treatment:
    Total removal:               2.57  percent
    Total biodegradation:        0.09  percent
    Total sludge adsorption:     1.90  percent
    Total to Air:                0.58  percent
      (using 10000 hr Bio P,A,S)

 Level III Fugacity Model:
           Mass Amount    Half-Life    Emissions
            (percent)        (hr)       (kg/hr)
   Air       5.31            93.7         1000       
   Water     36              360          1000       
   Soil      58.6            720          1000       
   Sediment  0.0896          3.24e+003    0          
     Persistence Time: 393 hr




        
(Details...) Spectra
Type: Near Infrared
Comments: public domain
Type: Infrared
Comments: public domain
Type: HNMR
Comments: public domain
Type: CNMR
Comments: public domain
(Details...) Feedback
DateSeverityStatusFeedback
10/17/2007 8:45:50 PMNormalFixedno Chloride so synonyms incorrect
Verdict: Fixed